Happenings

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08/12/20: Second lab paper published, but this was the first project started in lab! We studied how ‘free range’ engineered tissues grow in vitro and discovered some exciting biological principles of collective cell behavior and design rules of epithelial growth and assembly. Great fun working with Matt Heinrich, Dr. Ricard Alert, Prof. Andrej Kosmrlj and many others on this.

06/24/20: First lab paper published–SCHEEPDOG! A fantastic acronym from a fantastic team headlined by Dr. Tom Zajdel and Gawoon Shim. We use electrical cues to herd millimeter-scale tissues around a Petri dish proving that collective cell migration can literally be programmed.

01/14/20-05/20/20: The semester COVID first shut things down…CohenLab went into overdrive on COVID projects. We built 3000 PAPRs and a pandemic ventilator! More info forthcoming…

01/13/20:  Gawoon Shim passes her qualifying exam on bioelectric control of skin healing! Great way to start the new year!

12/20/19: First pre-print from the lab goes live! Check it out here where we literally herd cells using programmed bioelectric fields. Great work from Tom Zajdel, Gawoon Shim, Linus Wang, and Alex Rossello-Martinez!

12/06/19: Lisset Rosario passes her qualifying exam on waterbear biology! Great way to end the year!

08/01/19: Daniel receives an NIH MIRA award to fuel CohenLab’s work in collective cell behaviors and tissue interactions! Special thanks to NIH-NIGMS for R35-GM133574-01–what a great program new investigators!

06/05/19: CohenLab presented waterbears to the fantastic students of Harlem Prep on their visit to MAE. MAE hosted 65 students from Harlem Prep for a whirlwind series of demonstrations on science and engineering. We were happy to bring the biology with a discussion of why it’s so important to study even the strangest creatures and phenomena. And of course our ‘bears made an appearance.

Matt Heinrich educates the masses on waterbears.
Lisset Rosario captures a special moment for a waterbear: Low Reynolds Defecation.

05/16/19: Tower-to-Town Talks at Princeton Public Library! The last in our spring series, with talks from Daniel on how biology generates patterns, Prof. Luc Deike on ocean wave mechanics, and Dr. Tom Zajdel on the history of Radio!

The spotted claysnake–Daniel’s claymated example used to help explain Alan Turing’s theory of animal pattern formation!

04/18/19: Tower-to-Town Talks at Princeton Public Library! The second in our spring series, with talks from Daniel on the strange history of biomedical materials, Prof. Andrej Kosmrlj on flower mechanics, and Prof. Michelle Sarazen on the secret lives of chemical catalysts!

Dueling features heavily in motivating early Western rhinoplasty and reconstructive surgery (c. 1450s)

04/12/19: CohenLab at Dia de la Ciencia! The troops were out in force proselytizing for waterbears and the importance of ‘strange’ biology!

04/08/19: CohenLab goes to the APS March Meeting. Daniel presented on using swarm dynamics to engineer tissue behavior. Tom presented on our new tool to remotely control cell migration in real-time. Matt presented on strange, large-scale vortices in growing tissues. Julie showed our new approaches to extract epifluorescence-like data from phase contrast and DIC images!

04/01/19: MOL graduate student Lisset Duran Rosario joins the lab, co-advised with Prof. José Avalos. Welcome! Lisset is our resident tardigrade (waterbear!) expert and is in charge of Happy Moss Bear Farm in the Cohen Lab where she is studying both the biomechanics and cell biology of waterbears!

03/21/19: Tower-to-Town Talks at Princeton Public Library! The first in our new lecture series promoting crosstalk between university researchers and the local community. Each session, we’ll bring 3 speakers in to discuss their work in a public-friendly format! Our opening night features Daniel speaking about how history shapes modern bioelectricity research, graduate student Julie LaChance on how computer vision and machine learning work, and graduate student Evan Zhao on new developments in biofuel production.

Walk this way! 2 centuries after its publication, Frankenstein is still affecting science, but not necessarily in the way you might think!

The interregnum during which a baby is born and many things happen. 

T=0 of a longitudinal study.

03/01/19: MAE graduate student Gawoon Shim joins the lab. Welcome! Gawoon will be transitioning from work on wind-turbines to…the engineering the collective behavior of cells during skin and blood vessel formation!

Gawoon Shim
MAE Graduate Student

02/01/19: Alex Rosello Martinez joins the lab as a visiting Masters student from Imperial College London. Welcome! Alex will be working with Tom on programmable, bioelectric control of living cell migration.

12/01/18: CohenLab teaches high-school students about microfluidics and micro-organisms. We were happy to organize a workshop along with Prof. Michael Littman on new uses for old knowledge. Daniel lectured on biomechanics, bioelectricity, and extremophile biology, and the whole lab trained 50+ students from 9th-12th grade on how to make their own microfluidics and use them to look at tiny creatures like waterbears. We even developed a new technique for converting a hand-drawing in a microfluidic device in < 10 minutes!

10/01/18: Post-doctoral Fellow Dr. Tom Zajdel joins the lab to control cell behavior using electrical stimulation! Welcome, Tom!

06/10/18: CohenLab opens for business! It was so clean. But never fear, it didn’t stay that way.

Time to take it for a spin.

06/09/18: Matt Heinrich and Julie LaChance join the lab as the first students!
Little did they know what they were getting themselves into. Matt, co-advised with Prof. Andrej Kosmrlj, will be exploring the mechanics of tissue growth using new experimental approaches and lots of time-lapse microscopy! Julie will be applying her machine learning chops to better analyze giant datasets of the growth of giant tissues!

MAE Graduate Student
Co-advisor: Andrej Kosmrlj
Research: tissues as active soft matter
Julie M. LaChance
MAE Graduate Student
Research: machine learning for collective cell behavior